CD8(+) T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension

Recent studies suggest a role for T lymphocytes in hypertension. However, whether T cells contribute to renal sodium retention and salt-sensitive hypertension is unknown. Here we demonstrate that T cells infiltrate into the kidney of salt-sensitive hypertensive animals. In particular, CD8(+) T cells...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Liu, Yunmeng, Rafferty, Tonya M., Rhee, Sung W., Webber, Jessica S., Song, Li, Ko, Benjamin, Hoover, Robert S., He, Beixiang, Mu, Shengyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5227995/
https://ncbi.nlm.nih.gov/pubmed/28067240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14037
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky