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Genome-wide lethality screen identifies new PI4,5P(2) effectors that regulate the actin cytoskeleton
To further understand the roles played by the essential phosphoinositide PI4,5P(2), we have used a synthetic lethal analysis, which systematically combined the mss4(ts) mutation, partially defective in PI4P 5-kinase activity, with each of approximately 4700 deletion mutations. This genomic screening...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC522789/ https://ncbi.nlm.nih.gov/pubmed/15372071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600384 |
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