Integrated analysis of multiple biomarkers from circulating tumor cells enabled by exclusion-based analyte isolation

PURPOSE: There is a critical clinical need for new predictive and pharmacodynamic biomarkers that evaluate pathway activity in patients treated with targeted therapies. A microscale platform known as VERSA (Versatile Exclusion-based Rare Sample Analysis) was developed to integrate readouts across pr...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Sperger, Jamie M., Strotman, Lindsay N., Welsh, Allison, Casavant, Benjamin P., Chalmers, Zachery, Horn, Sacha, Heninger, Erika, Thiede, Stephanie M., Tokar, Jacob, Gibbs, Benjamin K., Guckenberger, David J., Carmichael, Lakeesha, Dehm, Scott M., Stephens, Philip J., Beebe, David J., Berry, Scott M., Lang, Joshua M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226928/
https://ncbi.nlm.nih.gov/pubmed/27401243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1021
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