Integrated analysis of multiple biomarkers from circulating tumor cells enabled by exclusion-based analyte isolation

PURPOSE: There is a critical clinical need for new predictive and pharmacodynamic biomarkers that evaluate pathway activity in patients treated with targeted therapies. A microscale platform known as VERSA (Versatile Exclusion-based Rare Sample Analysis) was developed to integrate readouts across pr...

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Publicado en:Clin Cancer Res
Autores principales: Sperger, Jamie M., Strotman, Lindsay N., Welsh, Allison, Casavant, Benjamin P., Chalmers, Zachery, Horn, Sacha, Heninger, Erika, Thiede, Stephanie M., Tokar, Jacob, Gibbs, Benjamin K., Guckenberger, David J., Carmichael, Lakeesha, Dehm, Scott M., Stephens, Philip J., Beebe, David J., Berry, Scott M., Lang, Joshua M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226928/
https://ncbi.nlm.nih.gov/pubmed/27401243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1021
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