Development of a Novel Enzyme-Linked Immunosorbent Assay Targeting a Neo-Epitope Generated by Cathepsin-Mediated Turnover of Type III Collagen and Its Application in Chronic Obstructive Pulmonary Disease

A high level of extracellular matrix (ECM) turnover characterizes several lung diseases with fibrotic features. Type III collagen is one of the most abundant collagens in lung parenchyma, and cathepsins play a role in lung pathology, being responsible for tissue remodeling. In this study, we explore...

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Publicat a:PLoS One
Autors principals: Rasmussen, Daniel Guldager Kring, Sand, Jannie Marie Bülow, Karsdal, Morten Asser, Genovese, Federica
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226775/
https://ncbi.nlm.nih.gov/pubmed/28076408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170023
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