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Reverse Pathway Genetic Approach Identifies Epistasis in Autism Spectrum Disorders
Although gene-gene interaction, or epistasis, plays a large role in complex traits in model organisms, genome-wide by genome-wide searches for two-way interaction have limited power in human studies. We thus used knowledge of a biological pathway in order to identify a contribution of epistasis to a...
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| Vydáno v: | PLoS Genet |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5226683/ https://ncbi.nlm.nih.gov/pubmed/28076348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006516 |
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