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Rapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory Drugs

Lymphocyte proliferation in response to antigenic or mitogenic stimulation is a readily quantifiable phenomenon useful for testing immunomodulatory (i.e., immunosuppressive or immunostimulatory) chemical compounds and biologics. One of the earliest steps during mitogenesis is cell enlargement or bla...

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Bibliografske podrobnosti
izdano v:J Vis Exp
Main Authors: Gibson, Jennifer N., Beesetty, Pavani, Sulentic, Courtney, Kozak, J. Ashot
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226628/
https://ncbi.nlm.nih.gov/pubmed/28060354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55212
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