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mTOR: An attractive therapeutic target for osteosarcoma?

Osteosarcoma (OS) is a common primary malignant bone tumor with high morbidity and mortality in children and young adults. How to improve poor prognosis of OS due to resistance to chemotherapy remains a challenge. Recently, growing findings show activation of mammalian target of rapamycin (mTOR), is...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ding, Liu, Congwei, Liu, Bei, Qing, Tao, Yang, Ruiguo, Wang, Heze, Yu, Bo, Dou, Zhihong, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226621/
https://ncbi.nlm.nih.gov/pubmed/27177330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9305
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