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SUMOylation of PES1 upregulates its stability and function via inhibiting its ubiquitination

PES1 is a component of the PeBoW complex, which is required for the maturation of 28S and 5.8S ribosomal RNAs, as well as for the formation of the 60S ribosome. Deregulation of ribosomal biogenesis can contribute to carcinogenesis. In this study, we showed that PES1 could be modified by the small ub...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Li, Shujing, Wang, Miao, Qu, Xinjian, Xu, Zhaowei, Yang, Yangyang, Su, Qiming, Wu, Huijian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226600/
https://ncbi.nlm.nih.gov/pubmed/27409667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10494
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