SUMOylation of PES1 upregulates its stability and function via inhibiting its ubiquitination

PES1 is a component of the PeBoW complex, which is required for the maturation of 28S and 5.8S ribosomal RNAs, as well as for the formation of the 60S ribosome. Deregulation of ribosomal biogenesis can contribute to carcinogenesis. In this study, we showed that PES1 could be modified by the small ub...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Shujing, Wang, Miao, Qu, Xinjian, Xu, Zhaowei, Yang, Yangyang, Su, Qiming, Wu, Huijian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226600/
https://ncbi.nlm.nih.gov/pubmed/27409667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10494
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