Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer

BACKGROUND: Notch pathway plays a complex role depending on cellular contexts: promotes stem cell maintenance or induces terminal differentiation in potential cancer-initiating cells; acts as an oncogene in lymphocytes and mammary tissue or plays a growth-suppressive role in leukemia, liver, skin, a...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Upadhyay, Pawan, Nair, Sudhir, Kaur, Ekjot, Aich, Jyotirmoi, Dani, Prachi, Sethunath, Vidyalakshmi, Gardi, Nilesh, Chandrani, Pratik, Godbole, Mukul, Sonawane, Kavita, Prasad, Ratnam, Kannan, Sadhana, Agarwal, Beamon, Kane, Shubhada, Gupta, Sudeep, Dutt, Shilpee, Dutt, Amit
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226594/
https://ncbi.nlm.nih.gov/pubmed/27391340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10419
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