Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1–NDRG1 axis in both PR-positive and -negative breast cancer cells

Preoperative progesterone intervention has been shown to confer a survival benefit to breast cancer patients independently of their progesterone receptor (PR) status. This observation raises the question how progesterone affects the outcome of PR-negative cancer. Here, using microarray and RNA-Seq–b...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Godbole, Mukul, Togar, Trupti, Patel, Kuldeep, Dharavath, Bhasker, Yadav, Neelima, Janjuha, Sharan, Gardi, Nilesh, Tiwary, Kanishka, Terwadkar, Prachi, Desai, Sanket, Prasad, Ratnam, Dhamne, Hemant, Karve, Kunal, Salunkhe, Sameer, Kawle, Dhananjay, Chandrani, Pratik, Dutt, Shilpee, Gupta, Sudeep, Badwe, Rajendra A., Dutt, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298595/
https://ncbi.nlm.nih.gov/pubmed/30337371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002894
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