Targeting synthetic lethality between the SRC kinase and the EPHB6 receptor may benefit cancer treatment

Application of tumor genome sequencing has identified numerous loss-of-function alterations in cancer cells. While these alterations are difficult to target using direct interventions, they may be attacked with the help of the synthetic lethality (SL) approach. In this approach, inhibition of one ge...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Paul, James M., Toosi, Behzad, Vizeacoumar, Frederick S., Bhanumathy, Kalpana Kalyanasundaram, Li, Yue, Gerger, Courtney, Zawily, Amr El, Freywald, Tanya, Anderson, Deborah H., Mousseau, Darrell, Kanthan, Rani, Zhang, Zhaolei, Vizeacoumar, Franco J., Freywald, Andrew
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226566/
https://ncbi.nlm.nih.gov/pubmed/27418135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10569
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