Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer

Cytochrome P450 (CYP) 1A1 is a phase I enzyme that can activate various compounds into reactive forms and thus, may contribute to carcinogenesis. In this study, we investigated the expression, methylation status, and functional role of CYP1A1 on prostate cancer cells. Increased expression of CYP1A1...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mitsui, Yozo, Chang, Inik, Kato, Taku, Hashimoto, Yutaka, Yamamura, Soichiro, Fukuhara, Shinichiro, Wong, Darryn K., Shiina, Marisa, Imai-Sumida, Mitsuho, Majid, Shahana, Saini, Sharanjot, Shiina, Hiroaki, Nakajima, Koichi, Deng, Guoren, Dahiya, Rajvir, Tanaka, Yuichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226494/
https://ncbi.nlm.nih.gov/pubmed/27203547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9470
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