Functional role and tobacco smoking effects on methylation of CYP1A1 gene in prostate cancer

Cytochrome P450 (CYP) 1A1 is a phase I enzyme that can activate various compounds into reactive forms and thus, may contribute to carcinogenesis. In this study, we investigated the expression, methylation status, and functional role of CYP1A1 on prostate cancer cells. Increased expression of CYP1A1...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Mitsui, Yozo, Chang, Inik, Kato, Taku, Hashimoto, Yutaka, Yamamura, Soichiro, Fukuhara, Shinichiro, Wong, Darryn K., Shiina, Marisa, Imai-Sumida, Mitsuho, Majid, Shahana, Saini, Sharanjot, Shiina, Hiroaki, Nakajima, Koichi, Deng, Guoren, Dahiya, Rajvir, Tanaka, Yuichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226494/
https://ncbi.nlm.nih.gov/pubmed/27203547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9470
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