Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency

In culture isolated bone marrow mesenchymal stem cells (more precisely termed skeletal stem cells, SSCs) spontaneously differentiate into fibroblasts, preventing the growth of large numbers of multipotent SSCs for use in regenerative medicine. However, the mechanisms that regulate the expansion of S...

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Vydáno v:Biomaterials
Hlavní autoři: Lee, Louisa C.Y., Gadegaard, Nikolaj, de Andrés, María C., Turner, Lesley-Anne, Burgess, Karl V., Yarwood, Stephen J., Wells, Julia, Salmeron-Sanchez, Manuel, Meek, Dominic, Oreffo, Richard O.C., Dalby, Matthew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226065/
https://ncbi.nlm.nih.gov/pubmed/27914982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.11.032
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