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Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency

In culture isolated bone marrow mesenchymal stem cells (more precisely termed skeletal stem cells, SSCs) spontaneously differentiate into fibroblasts, preventing the growth of large numbers of multipotent SSCs for use in regenerative medicine. However, the mechanisms that regulate the expansion of S...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Lee, Louisa C.Y., Gadegaard, Nikolaj, de Andrés, María C., Turner, Lesley-Anne, Burgess, Karl V., Yarwood, Stephen J., Wells, Julia, Salmeron-Sanchez, Manuel, Meek, Dominic, Oreffo, Richard O.C., Dalby, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226065/
https://ncbi.nlm.nih.gov/pubmed/27914982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.11.032
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