Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency

In culture isolated bone marrow mesenchymal stem cells (more precisely termed skeletal stem cells, SSCs) spontaneously differentiate into fibroblasts, preventing the growth of large numbers of multipotent SSCs for use in regenerative medicine. However, the mechanisms that regulate the expansion of S...

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Publicado en:Biomaterials
Autores principales: Lee, Louisa C.Y., Gadegaard, Nikolaj, de Andrés, María C., Turner, Lesley-Anne, Burgess, Karl V., Yarwood, Stephen J., Wells, Julia, Salmeron-Sanchez, Manuel, Meek, Dominic, Oreffo, Richard O.C., Dalby, Matthew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Science 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226065/
https://ncbi.nlm.nih.gov/pubmed/27914982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.11.032
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