Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency

In culture isolated bone marrow mesenchymal stem cells (more precisely termed skeletal stem cells, SSCs) spontaneously differentiate into fibroblasts, preventing the growth of large numbers of multipotent SSCs for use in regenerative medicine. However, the mechanisms that regulate the expansion of S...

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Udgivet i:Biomaterials
Main Authors: Lee, Louisa C.Y., Gadegaard, Nikolaj, de Andrés, María C., Turner, Lesley-Anne, Burgess, Karl V., Yarwood, Stephen J., Wells, Julia, Salmeron-Sanchez, Manuel, Meek, Dominic, Oreffo, Richard O.C., Dalby, Matthew J.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226065/
https://ncbi.nlm.nih.gov/pubmed/27914982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.11.032
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