Pmt-Mediated O Mannosylation Stabilizes an Essential Component of the Secretory Apparatus, Sec20p, in Candida albicans

Sec20p is an essential endoplasmic reticulum (ER) membrane protein in yeasts, functioning as a tSNARE component in retrograde vesicle traffic. We show that Sec20p in the human fungal pathogen Candida albicans is extensively O mannosylated by protein mannosyltransferases (Pmt proteins). Surprisingly,...

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Bibliografiske detaljer
Main Authors: Weber, Yvonne, Prill, Stephan K.-H., Ernst, Joachim F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC522601/
https://ncbi.nlm.nih.gov/pubmed/15470244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.5.1164-1168.2004
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