Quantification of rutin in rat's brain by UHPLC/ESI-Q-TOF-MS/MS after intranasal administration of rutin loaded chitosan nanoparticles

Rutin (RT), an antioxidant drug, has been utilized to treat cerebral ischemia hence a sensitive quantification method for estimation of RT in brain homogenate is necessary to develop. This study aims to prepare RT loaded Chitosan Nanoparticles (RT-CS-NPs) develop and validate ultra-high performance...

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Publicat a:EXCLI J
Autors principals: Ahmad, Niyaz, Ahmad, Rizwan, Naqvi, Atta Abbas, Alam, Md Aftab, Samim, Mohd, Iqbal, Zeenat, Ahmad, Farhan Jalees
Format: Artigo
Idioma:Inglês
Publicat: Leibniz Research Centre for Working Environment and Human Factors 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225736/
https://ncbi.nlm.nih.gov/pubmed/28096783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2016-361
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