Antibodies to poly[(2----8)-alpha-N-acetylneuraminic acid] and poly[(2----9)-alpha-N-acetylneuraminic acid] are elicited by immunization of mice with Escherichia coli K92 conjugates: potential vaccines for groups B and C meningococci and E. coli K1.

Meningitis and other systemic infections caused by group B Neisseria meningitidis and Escherichia coli K1 remain important problems. The capsular polysaccharides (CPs) of these pathogens (poly[(2----8)-alpha-N-acetylneuraminic acid] or poly(alpha 2-8NeuNAc] are identical and are virulence factors an...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Devi, S J, Robbins, J B, Schneerson, R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1991
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1908091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7175
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