Double targeted gene replacement for creating null mutants.

We have used double gene targeting to create homozygous gene replacements in the protozoan parasite Leishmania major, an asexual diploid. This method uses two independent selectable markers in successive rounds of gene targeting to replace both alleles of an endogenous gene. We developed an improved...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cruz, A, Coburn, C M, Beverley, S M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1991
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC52255/
https://ncbi.nlm.nih.gov/pubmed/1651496
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