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A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth in vivo

To create a new anti-tumor antibody, we conducted signal sequence trap by retrovirus-meditated expression method and identified coxsackie virus and adenovirus receptor (CXADR) as an appropriate target. We developed monoclonal antibodies against human CXADR and found that one antibody (6G10A) signifi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kawada, Manabu, Inoue, Hiroyuki, Kajikawa, Masunori, Sugiura, Masahito, Sakamoto, Shuichi, Urano, Sakiko, Karasawa, Chigusa, Usami, Ihomi, Futakuchi, Mitsuru, Masuda, Tohru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225458/
https://ncbi.nlm.nih.gov/pubmed/28074864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40400
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