Cigarette Smoke Mediates Nuclear to Cytoplasmic Trafficking of Transcriptional Inhibitor Kaiso through MUC1 and P120-Catenin

Lung cancer is the leading cause of cancer-related death, and 87% of these deaths are directly attributable to smoking. Using three-dimensional cultures of primary human bronchial epithelial cells, we demonstrated that loss of adherens junction protein, epithelial cadherin, and the aberrant interact...

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Vydáno v:Am J Pathol
Hlavní autoři: Zhang, Lili, Gallup, Marianne, Zlock, Lorna, Feeling Chen, Yu Ting, Finkbeiner, Walter E., McNamara, Nancy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2016
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225293/
https://ncbi.nlm.nih.gov/pubmed/27765636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.08.011
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