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Randomized phase II study of cetuximab versus irinotecan and cetuximab in patients with chemo-refractory KRAS codon G13D metastatic colorectal cancer (G13D-study)

PURPOSE: This study investigated the efficacy and safety of cetuximab-based treatment in patients with chemotherapy-resistant refractory mCRC with KRAS G13D mutation. PATIENTS AND METHODS: An assessment of the efficacy and safety of cetuximab-based treatment was performed in an observation-enriched...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Nakamura, Masato, Aoyama, Toru, Ishibashi, Keiichiro, Tsuji, Akihito, Takinishi, Yasutaka, Shindo, Yoshiaki, Sakamoto, Junichi, Oba, Koji, Mishima, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225170/
https://ncbi.nlm.nih.gov/pubmed/27878354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3203-7
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