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MCPIP1/Regnase-1 restricts IL-17A- and IL-17C-dependent skin inflammation ()

The IL-17-family cytokines IL-17A and IL-17C drive the pathogenesis of psoriatic skin inflammation, and anti-IL-17A Abs were recently approved to treat human psoriasis. To date, little is known about mechanisms that restrain IL-17 cytokine-mediated signaling, particularly IL-17C. Here, we show that...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Monin, Leticia, Gudjonsson, Johann E., Childs, Erin E., Amatya, Nilesh, Xing, Xianying, Verma, Akash H., Coleman, Bianca M., Garg, Abhishek, Killeen, Meaghan, Mathers, Alicia, Ward, Nicole L., Gaffen, Sarah L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225040/
https://ncbi.nlm.nih.gov/pubmed/27920272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601551
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