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IL-23 Inhibits Melanoma Development by Augmenting DNA Repair and Modulating T-cell Subpopulations

In animal models, IL-12 and IL-23 participate in the development of malignant neoplasms of keratinocytes. However, the role of these cytokines in pigmented lesion development and their progression to melanoma has received little attention. IL-12p35, IL-23p19, and IL-12/IL-23p40 knockout mice on a C3...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Nasti, Tahseen H., Cochran, J. Barry, Vachhani, Raj V, McKay, Kristopher, Tsuruta, Yuko, Athar, Mohammad, Timares, Laura, Elmets, Craig A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225020/
https://ncbi.nlm.nih.gov/pubmed/28003381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601455
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