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In vivo suppression of HSP27 and HSP70 accelerates DMBA-induced skin carcinogenesis by inducing antigenic unresponsiveness to the initiating carcinogenic chemical

Heat shock proteins (HSPs) are constitutively expressed in murine skin. HSP27 is present in the epidermis and HSP70 can be found in both the epidermis and dermis. The purpose of this study was to investigate the role of these proteins in cutaneous chemical carcinogenesis and to determine if their ef...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Yusuf, Nabiha, Nasti, Tahseen H., Ahmad, Israr, Chowdhury, Sanim, Mohiuddin, Hasan, Xu, Hui, Athar, Mohammad, Timares, Laura, Elmets, Craig A.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648556/
https://ncbi.nlm.nih.gov/pubmed/25840912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402804
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