The Mitochondrial Lon Protease is Required for Age-specific and Sex-specific Adaptation to Oxidative Stress

Multiple human diseases involving chronic oxidative stress show a significant sex bias, including neurodegenerative diseases, cancer, immune dysfunction, diabetes, and cardiovascular disease. However a possible molecular mechanism for the sex-bias in physiological adaptation to oxidative stress rema...

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Veröffentlicht in:Curr Biol
Hauptverfasser: Pomatto, Laura C.D., Carney, Caroline, Shen, Brenda, Wong, Sarah, Halaszynski, Kelly, Salomon, Matthew P., Davies, Kelvin J.A., Tower, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224972/
https://ncbi.nlm.nih.gov/pubmed/27916526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.10.044
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