Binding of the adenovirus VAI RNA to the interferon-induced 68-kDa protein kinase correlates with function.

In human cells infected with adenovirus, the virus-associated RNA VAI blocks the activation of the interferon-induced double-stranded-RNA-dependent 68-kDa protein kinase (p68) and maintains normal levels of protein synthesis at late times after infection. VAI antagonizes the kinase activity by bindi...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ghadge, G D, Swaminathan, S, Katze, M G, Thimmapaya, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52249/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1714589/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7140
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