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Binding of the adenovirus VAI RNA to the interferon-induced 68-kDa protein kinase correlates with function.

In human cells infected with adenovirus, the virus-associated RNA VAI blocks the activation of the interferon-induced double-stranded-RNA-dependent 68-kDa protein kinase (p68) and maintains normal levels of protein synthesis at late times after infection. VAI antagonizes the kinase activity by bindi...

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Autores principales: Ghadge, G D, Swaminathan, S, Katze, M G, Thimmapaya, B
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC52249/
https://ncbi.nlm.nih.gov/pubmed/1714589
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