Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis

BACKGROUND: Artemisinin-based combination therapies (ACTs) are the mainstay of the current treatment of uncomplicated Plasmodium falciparum malaria, but ACT resistance is spreading across Southeast Asia. Dihydroartemisinin-piperaquine is one of the five ACTs currently recommended by the World Health...

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Publicado en:PLoS Med
Main Authors: Hoglund, Richard M., Workman, Lesley, Edstein, Michael D., Thanh, Nguyen Xuan, Quang, Nguyen Ngoc, Zongo, Issaka, Ouedraogo, Jean Bosco, Borrmann, Steffen, Mwai, Leah, Nsanzabana, Christian, Price, Ric N., Dahal, Prabin, Sambol, Nancy C., Parikh, Sunil, Nosten, Francois, Ashley, Elizabeth A., Phyo, Aung Pyae, Lwin, Khin Maung, McGready, Rose, Day, Nicholas P. J., Guerin, Philippe J., White, Nicholas J., Barnes, Karen I., Tarning, Joel
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224788/
https://ncbi.nlm.nih.gov/pubmed/28072872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002212
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