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A double-strand break can trigger immunoglobulin gene conversion
All three B cell-specific activities of the immunoglobulin (Ig) gene re-modeling system—gene conversion, somatic hypermutation and class switch recombination—require activation-induced deaminase (AID). AID-induced DNA lesions must be further processed and dissected into different DNA recombination p...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5224512/ https://ncbi.nlm.nih.gov/pubmed/27701075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw887 |
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