Fbxo28 promotes mitotic progression and regulates topoisomerase IIα-dependent DNA decatenation

Topoisomerase IIα is an essential enzyme that resolves topological constraints in genomic DNA. It functions in disentangling intertwined chromosomes during anaphase leading to chromosome segregation thus preserving genomic stability. Here we describe a previously unrecognized mechanism regulating to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Kratz, Anne-Sophie, Richter, Kai T., Schlosser, Yvonne T., Schmitt, Miriam, Shumilov, Anatoliy, Delecluse, Henri-Jacques, Hoffmann, Ingrid
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224455/
https://ncbi.nlm.nih.gov/pubmed/27754753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1246093
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