Fbxo28 promotes mitotic progression and regulates topoisomerase IIα-dependent DNA decatenation

Topoisomerase IIα is an essential enzyme that resolves topological constraints in genomic DNA. It functions in disentangling intertwined chromosomes during anaphase leading to chromosome segregation thus preserving genomic stability. Here we describe a previously unrecognized mechanism regulating to...

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Publicado en:Cell Cycle
Autores principales: Kratz, Anne-Sophie, Richter, Kai T., Schlosser, Yvonne T., Schmitt, Miriam, Shumilov, Anatoliy, Delecluse, Henri-Jacques, Hoffmann, Ingrid
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224455/
https://ncbi.nlm.nih.gov/pubmed/27754753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1246093
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