Fbxo28 promotes mitotic progression and regulates topoisomerase IIα-dependent DNA decatenation

Topoisomerase IIα is an essential enzyme that resolves topological constraints in genomic DNA. It functions in disentangling intertwined chromosomes during anaphase leading to chromosome segregation thus preserving genomic stability. Here we describe a previously unrecognized mechanism regulating to...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Cycle
Hauptverfasser: Kratz, Anne-Sophie, Richter, Kai T., Schlosser, Yvonne T., Schmitt, Miriam, Shumilov, Anatoliy, Delecluse, Henri-Jacques, Hoffmann, Ingrid
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224455/
https://ncbi.nlm.nih.gov/pubmed/27754753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1246093
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