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Fbxo28 promotes mitotic progression and regulates topoisomerase IIα-dependent DNA decatenation

Topoisomerase IIα is an essential enzyme that resolves topological constraints in genomic DNA. It functions in disentangling intertwined chromosomes during anaphase leading to chromosome segregation thus preserving genomic stability. Here we describe a previously unrecognized mechanism regulating to...

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Библиографические подробности
Опубликовано в: :Cell Cycle
Главные авторы: Kratz, Anne-Sophie, Richter, Kai T., Schlosser, Yvonne T., Schmitt, Miriam, Shumilov, Anatoliy, Delecluse, Henri-Jacques, Hoffmann, Ingrid
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224455/
https://ncbi.nlm.nih.gov/pubmed/27754753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1246093
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