Repressor to activator switch by mutations in the first Zn finger of the glucocorticoid receptor: is direct DNA binding necessary?

Transfection of HeLa cells with cDNA vectors expressing the wild-type human glucocorticoid receptor (GR) enabled dexamethasone to strongly repress cytokine- and second messenger-induced expression of cotransfected chimeric reporter genes containing transcription regulatory DNA elements from the huma...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ray, A, LaForge, K S, Sehgal, P B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52238/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1871124/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7086
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