Endomorphin-2 Inhibition of Substance P Signaling within Lamina I of the Spinal Cord Is Impaired in Diabetic Neuropathic Pain Rats

Opiate analgesia in the spinal cord is impaired in diabetic neuropathic pain (DNP), but until now the reason is unknown. We hypothesized that it resulted from a decreased inhibition of substance P (SP) signaling within the dorsal horn of the spinal cord. To investigate this possibility, we evaluated...

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Dades bibliogràfiques
Publicat a:Front Mol Neurosci
Autors principals: Wan, Fa-Ping, Bai, Yang, Kou, Zhen-Zhen, Zhang, Ting, Li, Hui, Wang, Ya-Yun, Li, Yun-Qing
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223733/
https://ncbi.nlm.nih.gov/pubmed/28119567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00167
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