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The palmitoyltransferase Approximated promotes growth via the Hippo pathway by palmitoylation of Fat
The large protocadherin Fat functions to promote Hippo pathway activity in restricting tissue growth. Loss of Fat leads to accumulation of the atypical myosin Dachs at the apical junctional region, which in turn promotes growth by inhibiting Warts. We previously identified Approximated (App), a DHHC...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5223609/ https://ncbi.nlm.nih.gov/pubmed/28031421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201609094 |
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