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FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib

BACKGROUND: Sorafenib, a multi-kinase inhibitor, is used as a standard therapy for advanced hepatocellular carcinoma (HCC). However, complete remission has not been achieved and the molecular basis of HCC resistance to sorafenib remains largely unknown. Previous studies have shown that fibroblast gr...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Gao, Lixia, Wang, Xuli, Tang, Yaoliang, Huang, Shuang, Hu, Chien-An Andy, Teng, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223586/
https://ncbi.nlm.nih.gov/pubmed/28069043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0478-9
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