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FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib

BACKGROUND: Sorafenib, a multi-kinase inhibitor, is used as a standard therapy for advanced hepatocellular carcinoma (HCC). However, complete remission has not been achieved and the molecular basis of HCC resistance to sorafenib remains largely unknown. Previous studies have shown that fibroblast gr...

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Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Gao, Lixia, Wang, Xuli, Tang, Yaoliang, Huang, Shuang, Hu, Chien-An Andy, Teng, Yong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223586/
https://ncbi.nlm.nih.gov/pubmed/28069043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0478-9
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