The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition

Long interspersed elements 1 (L1) are active mobile elements that constitute almost 17% of the human genome. They amplify through a “copy-and-paste” mechanism termed retrotransposition, and de novo insertions related to these elements have been reported to cause 0.2% of genetic diseases. Our previou...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Servant, Geraldine, Streva, Vincent A., Derbes, Rebecca S., Wijetunge, Madushani I., Neeland, Marc, White, Travis B., Belancio, Victoria P., Roy-Engel, Astrid M., Deininger, Prescott L.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223499/
https://ncbi.nlm.nih.gov/pubmed/28049704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.188680
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