Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2

BACKGROUND: Taurine upregulated gene1 (TUG1) as a 7.1-kb lncRNA, has been shown to play an oncogenic role in various cancers. However, the biological functions of lncRNA TUG1 in small cell lung cancer (SCLC) remain unknown. The aim of this study is to explore the roles of TUG1 in cell growth and che...

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Publicado en:Mol Cancer
Autores principales: Niu, Yuchun, Ma, Feng, Huang, Weimei, Fang, Shun, Li, Man, Wei, Ting, Guo, Linlang
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223434/
https://ncbi.nlm.nih.gov/pubmed/28069000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0575-6
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