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Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease

Several studies reported an association between CSF alpha-synuclein (α-syn) and tau in Alzheimer’s disease (AD), and demonstrated the significance of α-syn in improving the diagnostic sensitivity/specificity of classical AD CSF biomarkers. In the current study, we measured CSF levels of different α-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Majbour, Nour K., Chiasserini, Davide, Vaikath, Nishant N., Eusebi, Paolo, Tokuda, Takahiko, van de Berg, Wilma, Parnetti, Lucilla, Calabresi, Paolo, El-Agnaf , Omar M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223278/
https://ncbi.nlm.nih.gov/pubmed/28071698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40263
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