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Regulatory T cells in cancer immunotherapy

FOXP3-expressing regulatory T (Treg) cells, which suppress aberrant immune response against self-antigens, also suppress anti-tumor immune response. Infiltration of a large number of Treg cells into tumor tissues is often associated with poor prognosis. There is accumulating evidence that the remova...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Res
Hauptverfasser: Tanaka, Atsushi, Sakaguchi, Shimon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223231/
https://ncbi.nlm.nih.gov/pubmed/27995907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.151
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