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Regulatory T cells in cancer immunotherapy

FOXP3-expressing regulatory T (Treg) cells, which suppress aberrant immune response against self-antigens, also suppress anti-tumor immune response. Infiltration of a large number of Treg cells into tumor tissues is often associated with poor prognosis. There is accumulating evidence that the remova...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Tanaka, Atsushi, Sakaguchi, Shimon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223231/
https://ncbi.nlm.nih.gov/pubmed/27995907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.151
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