Endothelin-1 Treatment Induces an Experimental Cerebral Malaria–Like Syndrome in C57BL/6 Mice Infected with Plasmodium berghei NK65

Plasmodium berghei ANKA infection of C57BL/6 mice is a widely used model of experimental cerebral malaria (ECM). By contrast, the nonneurotropic P. berghei NK65 (PbN) causes severe malarial disease in C57BL/6 mice but does not cause ECM. Previous studies suggest that endothelin-1 (ET-1) contributes...

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Udgivet i:Am J Pathol
Main Authors: Martins, Yuri C., Freeman, Brandi D., Akide Ndunge, Oscar B., Weiss, Louis M., Tanowitz, Herbert B., Desruisseaux, Mahalia S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2016
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222963/
https://ncbi.nlm.nih.gov/pubmed/27640146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.07.020
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