Tumor Cell-Independent Estrogen Signaling Drives Disease Progression Through Mobilization of Myeloid-Derived Suppressor Cells

The role of estrogens in anti-tumor immunity remains poorly understood. Here we show that estrogen signaling accelerates the progression of different estrogen insensitive tumor models by contributing to deregulated myelopoiesis by both driving the mobilization of myeloid-derived suppressor cells (MD...

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Pubblicato in:Cancer Discov
Autori principali: Svoronos, Nikolaos, Perales-Puchalt, Alfredo, Allegrezza, Michael J., Rutkowski, Melanie R., Payne, Kyle K., Tesone, Amelia J., Nguyen, Jenny M., Curiel, Tyler J., Cadungog, Mark G., Singhal, Sunil, Eruslanov, Evgeniy B., Zhang, Paul, Tchou, Julia, Zhang, Rugang, Conejo-Garcia, Jose R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222699/
https://ncbi.nlm.nih.gov/pubmed/27694385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0502
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