Clinicopathological and functional significance of RECQL1 helicase in sporadic breast cancers

RECQL1, a key member of the RecQ family of DNA helicases, is required for DNA replication and DNA repair. Two recent studies have shown that germ-line RECQL1 mutations are associated with increased breast cancer susceptibility. Whether altered RECQL1 expression has clinicopathological significance i...

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Gepubliceerd in:Mol Cancer Ther
Hoofdauteurs: Arora, Arvind, Parvathaneni, Swetha, Aleskandarany, Mohammed A, Agarwal, Devika, Ali, Reem, Abdel-Fatah, Tarek, Green, Andrew R, Ball, Graham R, Rakha, Emad A, Ellis, Ian O, Sharma, Sudha, Madhusudan, Srinivasan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222686/
https://ncbi.nlm.nih.gov/pubmed/27837030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0290
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