RECQL4 helicase has oncogenic potential in sporadic breast cancers

RECQL4 helicase is a molecular motor that unwinds DNA, a process essential during DNA replication and DNA repair. Germ-line mutations in RECQL4 cause type II Rothmund-Thomson syndrome (RTS) characterised by a premature aging phenotype and cancer predisposition. RECQL4 is widely considered as a tumou...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Arora, Arvind, Agarwal, Devika, Abdel-Fatah, Tarek MA, Lu, Huiming, Croteau, Deborah L., Moseley, Paul, Aleskandarany, Mohammed A, Green, Andrew R, Ball, Graham, Rakha, Emad A, Chan, Stephen YT, Ellis, Ian O, Wang, Lisa L, Zhao, Yongliang, Balajee, Adayabalam S., Bohr, Vilhelm A., Madhusudan, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576893/
https://ncbi.nlm.nih.gov/pubmed/26690729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4681
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