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Activating Receptors for Self-MHC Class I Enhance Effector Functions and Memory Differentiation of NK Cells during Mouse Cytomegalovirus Infection

Natural killer (NK) cells are important in host defense against pathogens, and they can subsequently differentiate into memory NK cells. The Ly49 and KIR gene families in rodents and humans encode both inhibitory and activating receptors for MHC class I. The physiological role of activating KIR or L...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunity
Hauptverfasser: Nabekura, Tsukasa, Lanier, Lewis L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222561/
https://ncbi.nlm.nih.gov/pubmed/27438766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.06.024
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